Safety Data Sheet — Tirzepatide (Lyophilized)¶

SECTION 1: Identification¶

Field	Detail
Product Name	Tirzepatide (Lyophilized Research Peptide)
Chemical Family	Synthetic Peptide / Biochemical Research Reagent
CAS Number	2023788-19-2
Supplier	RPL Peptide (Qingdao RPL Biotechnology Co., Ltd.)
Address	Qingdao, Shandong Province, China
Website	www.rplpeptides.com
Intended Use	Laboratory research use only — NOT for human/veterinary consumption

SECTION 2: Hazards Identification¶

GHS Classification: Not classified as hazardous in solid form under normal handling conditions.

Potential Hazards: - Dust/aerosol may cause respiratory irritation if inhaled - May cause eye irritation upon direct contact - Avoid ingestion — research compounds are not for consumption - Lyophilized peptide may be hygroscopic — protect from moisture

SECTION 3: Composition / Information on Ingredients¶

Component	Details
Active Ingredient	Tirzepatide (≥99.0% pure)
Counterion	Trifluoroacetic acid (TFA, CAS 76-05-1) — residual (<1%)
Water	Residual moisture (<5%)
Excipients	Mannitol or sucrose may be present (variable)

SECTION 4: First-Aid Measures¶

Route	Procedure
Inhalation	Move to fresh air. Seek medical attention if breathing difficulty persists.
Skin Contact	Wash with soap and water for 15 minutes. Remove contaminated clothing.
Eye Contact	Rinse with water for 15 minutes. Remove contact lenses. Seek medical attention if irritation persists.
Ingestion	Rinse mouth. Do NOT induce vomiting. Seek immediate medical attention.

SECTION 5: Fire-Fighting Measures¶

Parameter	Detail
Suitable Extinguishing Media	Water spray, dry chemical, CO₂, alcohol-resistant foam
Thermal Decomposition Products	CO, CO₂, NOx, HF

SECTION 6: Accidental Release Measures¶

Aspect	Procedure
Personal Precautions	Wear gloves, goggles, and lab coat. Avoid dust generation.
Spill Cleanup	Sweep or vacuum. Collect in sealed container. Dispose per local regulations.

SECTION 7: Handling and Storage¶

Handling: Use in ventilated laboratory. Wear PPE. Avoid dust generation. Wash hands after handling.

Storage: -20°C or 2–8°C in sealed vial. Protect from light and moisture.

SECTION 8: Exposure Controls / Personal Protection¶

Protection Type	Recommendation
Engineering Controls	Local exhaust ventilation recommended
Respiratory Protection	Not required under normal use. Dust mask if aerosol possible.
Hand Protection	Nitrile or latex gloves
Eye Protection	Safety goggles
Skin Protection	Lab coat

SECTION 9: Physical and Chemical Properties¶

Property	Value
Form	Lyophilized powder
Color	White to off-white
Odor	Odorless or slight acetic
pH (1% Solution)	4.0–6.5
Solubility	Water, PBS, saline
Melting Point	Decomposes >200°C
Flash Point	Not applicable

SECTION 10: Stability and Reactivity¶

Parameter	Detail
Stability	Stable under recommended storage conditions
Incompatibility	Strong oxidizing agents, strong acids/bases
Hazardous Decomposition	Thermal decomposition produces CO, CO₂, NOx, HF

SECTION 11: Toxicological Information¶

Endpoint	Detail
Acute Toxicity	Limited data. Handle as potentially irritating.
Skin	May cause mild irritation
Eye	May cause mechanical irritation
Respiratory	Avoid inhalation
Carcinogenicity	Not classified

SECTION 12: Ecological Information¶

Do not release into environment. Peptides are biodegradable. TFA residual is persistent.

SECTION 13: Disposal Considerations¶

Dispose according to local regulations. Incinerate at licensed facility. Do not dispose via drainage.

SECTION 14: Transport Information¶

Classification	Detail
UN Number	Not regulated
Hazard Class	Not classified as hazardous goods

SECTION 15: Regulatory Information¶

GHS: Not classified as hazardous in solid form
Label: Laboratory Research Use Only

SECTION 16: Other Information¶

Field	Detail
Issue Date	July 2026
Version	1.0
Prepared By	RPL Peptide Quality Department

This SDS is for informational purposes. Users should conduct their own risk assessment.

Official Technical Documentation

rplpeptides.com