RPL Peptide
Official Technical Documentation
Technical Data Sheet
Tirzepatide (GIP/GLP-1 Dual Agonist)¶
Product Overview¶
Tirzepatide is a synthetic 39-amino-acid dual receptor agonist peptide engineered to interact with both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor systems. It represents a class of multifunctional incretin receptor agonists designed for advanced metabolic research applications.
Product Specifications¶
| Parameter | Specification |
|---|---|
| Product Name | Tirzepatide |
| CAS Number | 2023788-19-2 |
| Synonyms | Dual GIP/GLP-1 Receptor Agonist Peptide |
| Amino Acid Count | 39 Amino Acids |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| Molecular Weight | ~4,813 Da |
| Peptide Type | Synthetic Modified Peptide |
| Classification | Dual Incretin Receptor Agonist |
| Appearance | White to Off-White Lyophilized Powder |
| Purity (HPLC) | ≥99.0% |
| Peptide Content | 70–90% |
| Water Content (KF) | <5% |
| Endotoxin | <5 EU/mg |
| Solubility | Soluble in water, PBS, saline |
| pH (1% Solution) | 4.0–6.5 |
| Storage (Lyophilized) | -20°C (2+ years) |
| Storage (4°C) | 12 months |
| Reconstituted Stability | 2–8°C for 30 days |
| Package Sizes | 5 mg, 10 mg, 20 mg, 50 mg vial |
| Certification | COA, HPLC, LC-MS |
Molecular Characteristics¶
- Molecular Class: Peptide-based dual GIP/GLP-1 receptor agonist
- Structural Features: Engineered peptide with modifications supporting multi-receptor interactions
- Mechanism of Interest: Coordinated activation of GIP and GLP-1 signaling pathways
- Research Category: Metabolic research peptides, incretin biology
Quality Assurance¶
Each batch is tested using validated analytical methods:
- HPLC purity analysis at 214 nm
- LC-MS molecular weight confirmation (±0.5 Da)
- UPLC chromatographic profiling
- Water content by Karl Fischer (KF)
- Endotoxin testing (LAL method)
- Batch-specific Certificate of Analysis (COA)
- Third-party analytical validation available upon request
Reconstitution Protocol¶
- Equilibrate vial to room temperature (15–25°C).
- Briefly centrifuge to collect powder at vial bottom.
- Add bacteriostatic water (0.9% benzyl alcohol) against inner wall.
- Swirl gently — DO NOT vortex or shake vigorously.
- Clear solution = complete reconstitution.
- Recommended concentration: 1–5 mg/mL.
Regulatory & Disclaimer¶
This product is for laboratory research use only. NOT for human or veterinary consumption, medical treatment, diagnosis, or therapeutic application. All research must comply with applicable regulations.
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Official Technical Documentation
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